nature & planetanalysisThe Conversation
‘Mad honey’ that can stop your heart is now being sold online worldwide
Mad honey is made by the Himalayan cliff bee, the world's largest honeybee, which forages on rhododendron flowers that produce grayanotoxin, a natural toxin. The bees tolerate it, but people do not: a tablespoon or more can slow the heart dangerously and drop blood pressure within 30 to 60 minutes. Doctors treat poisoning with intravenous fluids and atropine, and most patients recover within a day or two. Many poisonings occur because people eat the honey deliberately as a remedy for high blood pressure or to improve sexual function, and the dose that helps is very close to the dose that harms. Toxin levels peak in spring, when the main harvest happens, and the honey is now sold internationally online, often without warnings.
Rhododendron flowers make grayanotoxin, which likely deters insects that steal nectar without pollinating. The toxin passes into the honey, where it concentrates. In humans it disrupts the electrical signals that control heartbeat, so the heart slows and blood pressure falls.
A traditional remedy with real pharmacological effects has become a global product, and buyers who have never encountered it can end up in intensive care. Dangerous plant chemistry reaching far from its origin is a growing public health issue.
background
Mad honey is honey that contains grayanotoxins. The dark, reddish honey is produced from the nectar and pollen of genus Rhododendron and has both toxic and narcotic effects.
Mad honey is produced principally in Nepal and Turkey, where it is used both as a traditional medicine and a recreational drug. In the Himalayan range, it is produced by Himalayan giant honey bees (Apis laboriosa). The Gurung people of Nepal have practiced wild honey hunting as a sacred ancient tradition for generations. The honey can also be found rarely in the eastern United States.
Historical accounts of mad honey are found in Ancient Greek texts. The Greek military leader Xenophon wrote in his Anabasis about the effects of mad honey on soldiers in 401 BCE. In 65 BCE, during the Third Mithridatic War, King Mithridates used mad honey in a mass poisoning campaign against Pompey's soldiers. During the 18th century, mad honey was imported to Europe where it was added to alcoholic beverages.
From Wikipedia: Mad honey (CC BY-SA 4.0) ↗Illustrative photo · The Drug Users Bible, CC BY 2.0, via Wikimedia Commons
