historyThe Public Domain Review1667 · London

In 1667 a London man received sheep's blood in the first English human transfusion

the gist

In November 1667, the physician Richard Lower and Edmund King carried out the first recorded human blood transfusion in England, at Arundel House in London. They first drew arterial blood from a sheep through a silver pipe and then fed about 9 to 10 ounces of it into a vein in the arm of Arthur Coga, a Cambridge divinity student who was paid a guinea. Lower described Coga as having a mild form of madness and hoped the gentle nature of a lamb would calm him. Coga felt well afterwards and wrote an account in Latin, but a second transfusion did not change his temper. The experiment was reported to the Royal Society.

how it works

The doctors connected an artery of a sheep to a vein in the man's arm with silver pipes and quills. The blood flowed by gravity and the heart's pulse, and the team could feel a pulse through the pipe. They judged the quantity from the sheep's blood lost in a minute.

so what

The experiment was part of the early effort to find out whether blood could be moved between animals and people, a question that later led to the understanding of blood groups. The same year, transfusions were tried in France, and they were soon banned in several countries because of the risks.

more on this

background

Blood transfusion refers to the intravenous transfer of blood products into a human or other animal. Apart from the setting of major trauma, whole blood is rarely transfused in modern practice. Instead, only components of the blood, such as red blood cells, plasma, platelets, and other clotting factors are transfused. White blood cells are not commonly transfused, since granulocyte transfusion has limited applications.

From Wikipedia: Blood transfusion (CC BY-SA 4.0) ↗

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