mind & bodyScienceDaily

The brain’s hidden fear mechanism may explain anxiety and PTSD

from ScienceDaily

A surprising new discovery suggests that fear may cause the brain to blur the line between danger and safety rather than distinguish them more clearly. By observing brain activity in mice using augmented reality, scientists found that memories of threatening and harmless environments began to overlap, potentially allowing faster responses to danger. This "better safe than sorry" survival mechanism could help explain why people with anxiety or PTSD sometimes experience intense fear in completely safe situations.

explained

Post-traumatic stress disorder (PTSD) is a mental disorder that develops from experiencing a traumatic event. Examples include sexual assault, domestic violence, child abuse, warfare along its associated traumas, natural disaster, bereavement, traffic collision, or other traumatic events on a person's life or well-being. Symptoms may include disturbing thoughts, feelings, or dreams related to the events, mental or physical distress to trauma-related cues, attempts to avoid trauma-related cues, alterations in the way a person thinks and feels, and an increase in the fight-or-flight response. These symptoms last for more than a month after the event and can include triggers such as misophonia. Young children are less likely to show distress, but instead may express their memories through play.

Most people who experience traumatic events do not develop PTSD. People who experience interpersonal violence such as rape, other sexual assaults, being kidnapped, stalking, physical abuse by an intimate partner, and childhood abuse are more likely to develop PTSD than those who experience non-assault based trauma, such as accidents and natural disasters. In the United States, about 3.5% of adults have PTSD in a given year, and 9% of people develop it at some point in their lives. In much of the rest of the world, rates during a given year are between 0.5% and 1%. Higher rates may occur in regions of armed conflict. It is more common in women than men.

From Wikipedia: Post-traumatic stress disorder (CC BY-SA 4.0) ↗
so what

It shifts the picture of anxiety from a failure to tell safe from unsafe to a survival bias that has gone too far. That may point to new treatments, though this is mouse research.

fun fact

The amygdala, a small almond-shaped brain region, is central to fear learning.

more on this

Illustrative photo · Unknown author, CC BY 4.0, via Wikimedia Commons