Eroom's law describes the puzzling trend that drug discovery keeps getting slower and more expensive even as the tools improve. Techniques such as high-throughput screening, biotechnology and computer-aided drug design have all arrived, yet the inflation-adjusted cost of bringing a new drug to market roughly doubles about every nine years. The pattern was first noticed in the 1980s. The name is Moore's law spelled backwards, a deliberate contrast with the way computing power, as in transistor counts, grows exponentially. The term was coined by Jack Scannell and colleagues in a 2012 paper in Nature Reviews Drug Discovery. Researchers still debate the causes, which include tougher safety standards, easy targets already being used up, and more complex regulation.

Hampi is a UNESCO World Heritage Site in Karnataka, India, with more than 1,600 surviving remains spread over 4,100 hectares. It was the capital of the Vijayanagara Empire from 1336 to 1565. Travellers from Persia and Portugal described it as a prosperous, wealthy and grand city with temples, markets and farms along the Tungabhadra River. By 1500 it was estimated to be the world's second-largest city after Beijing, and probably India's richest at the time. In 1565 a coalition of Muslim sultanates defeated the Vijayanagara Empire, its capital was conquered and destroyed, and the city was left in ruins. Hampi remains a religious centre, with the active Virupaksha Temple at its heart.