Low testosterone linked to 18% higher risk of dying from cancer

from ScienceDaily

A major international study tracking more than 26,000 men found that very low testosterone levels were associated with an 18% higher risk of dying from cancer later in life. Surprisingly, testosterone itself showed no clear link to prostate cancer, although two other sex hormones did. Researchers believe low testosterone could be an important early warning sign of future health risks, particularly when levels fall below 8.6 nmol/L.

explained

Testosterone is the primary male sex hormone and androgen in males. In humans, testosterone drives the development of male reproductive tissues such as testicles and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair. It is associated with increased aggression, sex drive, dominance, courtship display, and a wide range of behavioral characteristics. In addition, testosterone in both sexes is involved in health and well-being, where it has a significant effect on overall mood, cognition, social and sexual behavior, metabolism and energy output, the cardiovascular system, and in the prevention of osteoporosis. Insufficient levels of testosterone in men may lead to abnormalities including frailty, accumulation of adipose fat tissue within the body, anxiety and depression, sexual performance deficits, and bone loss.

Excessive levels of testosterone in men may be associated with hyperandrogenism, higher risk of heart failure, increased mortality in men with prostate cancer, and male pattern baldness.

From Wikipedia: Testosterone (CC BY-SA 4.0) ↗

so what

Hormone blood tests could one day flag men at higher long-term risk before disease appears. It also shows that sex hormones matter for health in ways that go beyond fertility and muscle.

D. W. Griffith’s A Corner in Wheat (1909)

the gist

In 1909 D. W. Griffith made a 14-minute film about a speculator who corners the wheat market and doubles the price of bread. A farmer sows his field while a 'Wheat King' gambles in the Chicago wheat pit; bakers raise the loaf from five cents to ten and the poor line up for bread. Griffith cut back and forth between the farm, the feast and the breadline, a technique called parallel editing, so audiences saw both ends of the economy at once. The film drew on Frank Norris's stories and on a real scheme: months earlier Chicago financier James Patten had cornered wheat, sent bread prices up and made about $5 million, roughly $185 million today.

how it works

To corner a market, a trader buys up most of the available supply and the futures contracts that promise more. Anyone who has to deliver the commodity must then buy from the cornerer at whatever price is demanded. The trader profits until the stock is released or the scheme collapses.

so what

A century on, it still shows how markets can be rigged by someone who controls supply, and how the people at either end, farmers and eaters, pay for it. It also helped establish editing as a way to argue a point, not just tell a story.

the bigger pattern

Corners have recurred whenever supply could be locked up, from the Hunt brothers' attempt on silver in 1979 to 1980 to the 'Black Friday' gold panic of 1869. Many such schemes end by collapsing, and the response is often new rules on speculation.

fun fact

In the film the Wheat King dies by falling into a grain elevator and being buried in the wheat he hoarded, an ending borrowed from Norris's novel The Octopus.

Usman Khawaja refuses to answer Sandpapergate question about Pat Cummins | 7.30

from ABC News In-depth

One of the darkest days in Australia's sporting history has been dragged back into the spotlight.

A new autobiography by former Test cricketer Usman Khawaja has made explosive revelations about the Australian Test team's 2018 ball-tampering saga in South Africa.

7.30 host Sarah Ferguson speaks to Usman Khawaja.

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