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mind & bodyanalysisKnowable Magazine

Dogs, devils, clams and catfish: When cancer is contagious

the gist

Cancer is normally not infectious, but in a few animals tumour cells themselves pass between individuals like a parasite. Canine transmissible venereal tumour has spread among dogs for thousands of years, transferring during mating, and is effectively one cancer cell line that has outlived its original host. Tasmanian devils suffer from facial tumours spread by biting, which since the 1990s have devastated their populations. Some clams and other shellfish have contagious leukaemia-like cancers. These cases challenge the neat definitions of an individual, a disease and a parasite, since the cancer cells are a separate lineage living in other animals.

so what

Studying contagious cancers shows how cancer cells can evade the immune system, a key question in human cancer research. It also raises conservation challenges for species like the devil.

fun fact

The dog cancer is the oldest known continuously surviving cancer lineage, with an origin estimated at several thousand years ago.

more on this

background

A transmissible cancer is a cancer cell or cluster of cancer cells that can be transferred between individuals without the involvement of an infectious agent such as an oncovirus. The evolution of transmissible cancer has occurred naturally in other animal species, but human cancer transmission is rare. This transfer is typically between members of the same species or closely related species.

From Wikipedia: Clonally transmissible cancer (CC BY-SA 4.0) ↗

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