science & techWellcome Collection

A human starts as a single cell and reaches the first breath in roughly nine months of steps

the gist

A pregnancy begins when a sperm releases its 23 chromosomes into the egg, and the egg then forms a hard capsule that blocks any other sperm. The fertilised cell is nudged down the fallopian tube while copying its DNA. By about week three the embryo is a flat disc with two fluid-filled sacs, one of which becomes the yolk sac that makes the first blood cells. By week four a heart tube is beating and the nerve tube is forming in the head. Around week five the embryo has a tail, which later shrinks away, while the sexes begin to differentiate in the third month. By the sixth month a baby can be born early, though survival is low at that stage. At full term the lungs must be ready for air, which is why birth is the start of breathing.

so what

Understanding these stages explains why early pregnancy is so vulnerable and why premature birth carries such risk. It also shows how much of the body is built in the first weeks, before most people know they are pregnant.

fun fact

The coccyx at the base of the spine is what remains of the tail that the human embryo develops early on.

Wellcome Collection · CC BY 4.0

Illustrative photo · Zephyris, CC BY-SA 3.0, via Wikimedia Commons