nature & planetanalysisGlobal Voices: Food

A fungus toxin in maize and peanuts quietly drives liver cancer in East Africa

the gist

Aflatoxins are poisons made by Aspergillus moulds that grow on stored staples such as maize, groundnuts, cottonseed and tree nuts, especially when it is warm and humid. They are tasteless and odourless, so people usually cannot tell a contaminated crop by looking or smelling it. Long-term exposure damages liver cells and reduces their ability to repair themselves, and the cancer can take 10 to 15 years to appear. Research in Africa has linked at least 40 percent of liver cancers to aflatoxin exposure. Drought and heat stress on crops make contamination more likely, which is why it is rising in East Africa.

how it works

The Aspergillus fungi grow in soil and infect crops in the field, and they spread most when plants are stressed by drought or heat. Once a crop is stored damp or damaged, the fungus keeps producing the toxin. The body breaks the toxin down into a compound that binds to DNA in liver cells, causing damage that builds up over years. Biocontrol products such as Aflasafe work by filling the field with harmless fungal strains that crowd out the toxic ones.

so what

Aflatoxin is one of the clearest examples of a food safety problem that is invisible, slow and deadly, and it hits the regions where people depend most on a few staple crops. Climate change is making the fungus more common, so it links food security with cancer risk. Most of the damage can be prevented with drying, careful harvesting and protecting grain from insects.

more on this

background

Aflatoxins are various poisonous carcinogens and mutagens that are produced by certain molds, especially Aspergillus species such as Aspergillus flavus and Aspergillus parasiticus. According to the USDA, "They are probably the best known and most intensively researched mycotoxins in the world." The fungi grow in soil, decaying vegetation and various staple foodstuffs and commodities such as hay, maize (corn), peanuts, coffee, wheat, millet, sorghum, cassava, rice, chili peppers, cottonseed, tree nuts, sesame seeds, sunflower seeds, and various cereal grains and oil seeds. They have been found in both pet and human foods, as well as in feedstocks for agricultural animals. Animals fed contaminated food can pass aflatoxin transformation products into milk, milk products, and meat. For example, contaminated poultry feed is the suspected source of aflatoxin-contaminated chicken meat and eggs in Pakistan.

From Wikipedia: Aflatoxin (CC BY-SA 4.0) ↗ · text CC BY-SA 4.0

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Illustrative photo · CCoil ( talk ), CC BY-SA 3.0, via Wikimedia Commons